My daughter is left handed and she also loves to drive R/C cars with dad and her brother. To make sure she has a good experience, she needs the appropriate tools. I’ve seen several lefties use standard right-handed transmitters. They hold the grip in their right hand to work the trigger, and the steering wheel faces away, so they reach around the front to work the steering with their left hand.
My left-handed daughter instinctively did just this with a normal transmitter (Tx). Even at only 5 years old, her brain told her to steer with her dominant hand. While it works for many, it’s unfortunate. Left-handed transmitters are not widely available for people entering the hobby, so they try to make it work with a right-handed Tx. By the time they can afford a model that can be converted to left-handed, they’ve already gotten used to contorting themselves, so what should seem natural feels strange.